Abstract
ObjectiveTo estimate the seroprevalence of SARS-CoV-2 antibodies in the Valencian Community (Spain) in October 2022, when BA.5 was the predominant variant. MethodCross-sectional, region-wide, population-based serosurvey study in 88 randomly selected primary care centers of the Valencian Community. ResultsSeroprevalence of anti-nucleocapsid (indicative of past infection) and total receptor binding domain (indicative of past infection or vaccination) antibodies was 71.0% (confidence interval [CI]: 67.8-74.2) and 98.4% (CI: 97.5-99.3), respectively. 66.7% (CI: 63.4-70.0) of the population shows hybrid immunity, but only 43.2% in those 80 and over. ConclusionsThe high proportion of hybrid immunity detected is relevant for public health strategies. A second vaccination booster was advisable in the elderly population.
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