Seroprevalence of anti-SARS-CoV-2 total antibodies among COVID-19 patients in province of Punjab, Pakistan

Abstract

At the end of 2019, there was an outbreak of coronavirus in Wuhan, China which killed more than 1800 people and more than 70,000 people were infected during the first 5 days. Chinese researchers named it as a novel coronavirus disease 2019. Up to now, 231 million cases and more than 4 million deaths have been reported worldwide. The total number of cases of COVID cases in Pakistan was 1,236,888 so far and the total death toll was 27,500 and is increasing rapidly. OmniPATHTM COVID-19 Total Antibody ELISA Test kit was used for serological analysis. We found that the highest number of patients with positive antibody test was Lahore with 48%. (n=442). Total antibodies against SARS-CoV-2 was found to be higher in men (43%) compared to women (41%). 13% of the children were found to be positive for SARS-CoV-2 IgG. In age wise distribution, patients in age group 41-50 year were recorded highest seroprevalance. We took the mean of antibody titer according to different age groups and we found the highest mean of antibody titer which was 171 in age group (21-30).