Abstract
Sera from over 200 hospital patients were examined for brucella antibodies by conventional agglutination tests and by newly suggested methods. Since these new methods mainly depend on the detection of microglobulins (IgG) which reflect activity of the infection, they have been found to be of particular help in the clinically doubtful case of the disease. Sera from healthy adults and children or from uninfected hospital patients rarely possess these antibodies except in low titre. Detailed results are given for 8 out of 16 cases in adults and 8 of 12 acute cases in children. Complement-fixation and anti-human-globulin tests may usefully be employed in surveillance of patients after apparent recovery from an acute attack of the infection. We have confirmed that in some cases of chronic brucellosis these tests are indispensable.
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