Abstract
SummaryAntigenic relationships between infectious canine hepatitis virus (ICHV) and certain human adenoviruses have been confirmed by complement-fixation, indirect hemagglutination and gel-diffusion precipitin tests. The serological relationship was unilateral, since antisera against human adenoviruses react in various tests with ICHV antigen, while specific antisera to ICHV failed to react with group-reactive human adenovirus antigens (types 2 and 4). There was no specific cross-neutralization between ICHV and the adenovirus types examined. Certain biologic properties shared by ICHV and the human adenoviruses have been compared, and these suggest that ICHV should be included taxonomically within the adenovirus group.
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