Abstract
Enzyme-linked immunosorbent assay, Western blot, and virus neutralization assays indicated that red colobus monkeys in Kibale National Park, western Uganda, had antibodies to a virus that was similar, but not identical, to known orthopoxviruses. The presence of a novel poxvirus in this endangered primate raises public health and conservation concerns.
Highlights
The virus subfamily Chordopoxviridae contains emerging pathogens of considerable concern, both because of their historic impact on global human health and because of their zoonotic potential [1]
vaccinia virus (VV)-reactive antibodies were detected with horseradish peroxidase (HRP)–conjugated polyclonal goat anti–rhesus macaque (RM; Macaca mulatta) immunoglobulin (Ig) G (Fc specific; Nordic Laboratories, Tilsbug, the Netherlands), which readily detected antibodies of other primate species, including red colobus monkeys and humans
Plasma samples from all 31 red colobus were tested, and all exhibited a neutralizing titer 50 of
Summary
The virus subfamily Chordopoxviridae contains emerging pathogens of considerable concern, both because of their historic impact on global human health and because of their zoonotic potential [1]. The Study From June 12 to June 24, 2006, 31 red colobus (13 males, 18 females, all adult or subadult) were sampled from Kibale National Park, western Uganda [5,6].
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