Abstract
Serogroup A Neisseria meningitidis outside meningitis belt in southwest Cameroon.
Highlights
We report an epidemic of meningococcal meningitis in the South-West Province of Cameroon (~500 km south of the African meningitis belt and 350 km east of Yaoundé, the country’s capital), involving 61 cases and 13 (21%) deaths
The third pandemic caused by this strain began in China in 1993, causing large epidemics in Mongolia in 1994 and Moscow in 1996 [4]. This sequence type seemed to emerge in Africa since 1995 [5], and researchers hypothesized that severe epidemics attributable to this ST-7 clone occurred in Cameroon and Niger, since such strains were circulating in the population and this ST-7 clone was responsible for severe outbreaks in Chad (1998) and Sudan (1999) [5]
We showed that in 1999 to 2000 in Yaoundé, a large city situated in the tropical rainforest at about 600 km south of the meningitis belt, N. meningitidis was isolated in 13.4% of cases of bacterial meningitis, and most of the strains isolated belonged to serogroup A [3]
Summary
8. Mølbak K, Varma J, Rossiter S, Lay J, Joyce K, Stamey K, et al Antimicrobial resistance in Salmonella serotype Typhimurium, R-type ACSSuT, is associated with bacteremia; NARMS, 1996-2000. In the countries within the meningitis belt, the illness is endemic and sporadic: numerous cases of meningococcal meningitis are reported each year during the dry season, and every 6–12 years a large outbreak occurs.
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