Abstract
Aims: Toxoplasma gondii is a protozoan parasite and congenital transmission, abortion, and prenatal mortality are major problems of this parasite. This study was carried out to determine the seroprevalence of Toxoplasma infection in the pregnant women, referring to Khoy Public Hospital, Iran, during 2015–2017. Materials and Methods: In this descriptive cross-sectional study, 3 ml of venous blood were taken from 1060 pregnant women and centrifuged; the collected sera were kept in a freezer at -20°C until testing. Then, samples were examined for the presence of IgG and IgM Toxoplasma antibodies using Autobio ELISA kit according to manufacturer's instructions. Data analysis was done using Chi-square test and SPSS-10 software. Results: Among 1060 serum samples of pregnant women, 38.2% were positive for anti-T. gondii antibodies. IgG and IgM titers of antibodies to T. gondii were positive in 36.6% and 1.2% of women, respectively. The incidence in women older than 30 years was 49.3%. The positive rate of IgG of pregnant women increased with age (P < 0.05). In women who were living in the village, the prevalence was 45.5% and in urban women, it was 21.5%; this difference was statistically significant (P < 0.05). Conclusion: The relatively high prevalence of T. gondii infection in this study showed that pregnant women infected with this parasite at an early age and it is important for pregnant women to prevent irreversible complications in neonates.
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