Abstract
Seroepidemiology of Saffold Cardiovirus Type 2
Highlights
The outcome can be explained by a short duration of virus excretion in stool, which, is unlikely for an infection spreading by the fecal–oral route
It may be that the virus is unstable in stool and rapidly degrades, such that fecal samples are inadequate for diagnosis of the infection
The study with a high prevalence of positive stool samples made use of primers selected in a conserved region of 2C helicase [5], whereas other studies used primers in the 5′ noncoding region [3,4]
Summary
The outcome can be explained by a short duration of virus excretion in stool, which, is unlikely for an infection spreading by the fecal–oral route. Collected SAFV-2 pos‡ SAFV-3 pos‡ SAFV pos§ SAFV-3 neg SAFV-3 pos Netherlands mo 2006–2007 [52] *SAFV, Saffold virus; pos, positive; neg, negative.
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