Seroepidemiology of pandemic influenza A (H1N1) 2009 virus infections in northern Greece

Georgia Gioula,Angeliki Melidou,Nikolaos Malisiovas,Dimitrios Chatzidimitriou,E Diza-Mataftsi,Maria Exindari,M Pape

doi:10.29333/ejgm/82752

Abstract

In case cross-reactivity against the 2009 pandemic in- fluenza virus is indeed due to infections caused by the Spanish influenza and /or its immediate descendant viruses in the late 1910s and the 1920s, this would seem to suggest that specific anti-influenza immunity can last for an extremely long time, even a lifetime. A recent study showing the existence of B cells clones specific for the Spanish influenza HA in the elderly, in- dicate that immunological memory may last a whole lifetime (9). Among the 400 post-pandemic specimens tested, the seroprevalence was 34,5% (n=138), while 53,6% of them were females. The mean age of the se

Highlights

Specimens belonged to 60 people living in Thessaloniki and 25 inhabitants of other parts of northern Greece
It is important to pinpoint that all specimens belonged to unvaccinated individuals, of both seasonal and pandemic H1N1 influenza virus
The multivariate logistic regression model was used to investigate the potential correlative factors that influenced the frequency and distribution of pandemic H1N1 antibodies in different groups

Summary

Introduction

Post-pandemic (age groups) specimens belonged to 60 people living in Thessaloniki and 25 inhabitants of other parts of northern Greece. Of the 400 samples, 320 were collected from inhabitants of Thessaloniki, 80 from people living in other parts of northern Greece. It is important to pinpoint that all specimens belonged to unvaccinated individuals, of both seasonal and pandemic H1N1 influenza virus.

Results

Conclusion