Abstract

Serodiscordant twins: A case report of vertical HIV transmission during PMTCT option B+ role out

Highlights

  • We describe a case of discordant dizygotic (DZ) Human Immunodeficiency Virus (HIV)-exposed twins

  • We describe a case of discordant dizygotic (DZ) HIV-exposed twins

  • This is a recording of Prevention of Mother to Child Transmission (PMTCT) and Early Infant Diagnosis (EID) and their unrivalled success in HIV management

Read more

Summary

Introduction

We describe a case of discordant dizygotic (DZ) HIV-exposed twins. This is a recording of Prevention of Mother to Child Transmission (PMTCT) and Early Infant Diagnosis (EID) and their unrivalled success in HIV management. Initial unequivocal evidence came to light that to introduce antiretroviral therapy (ART) at CD4 levels of 350 - 500 cells × 109/L in all adults, including pregnant women is beneficial for mortality and morbidity outcomes [2,3]. It follows naturally that the earlier the initiation of ART takes place in pregnancy, the lower is the risk of HIV transmission to the infant. Due to earlier ART initiation the proportion of pregnant women living with HIV in South Africa on ART increased from 83% in 2009 to 87% in 2012 [4]. It is suggested that 10% of neonates who have HIV infection contract it in utero, 60% are infected peri- or intra-partum, while 30% of infants acquire HIV postnatally [5,6]

Objectives
Discussion
Conclusion
Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.