Abstract
Serodiscordant twins: A case report of vertical HIV transmission during PMTCT option B+ role out
Highlights
We describe a case of discordant dizygotic (DZ) Human Immunodeficiency Virus (HIV)-exposed twins
We describe a case of discordant dizygotic (DZ) HIV-exposed twins
This is a recording of Prevention of Mother to Child Transmission (PMTCT) and Early Infant Diagnosis (EID) and their unrivalled success in HIV management
Summary
We describe a case of discordant dizygotic (DZ) HIV-exposed twins. This is a recording of Prevention of Mother to Child Transmission (PMTCT) and Early Infant Diagnosis (EID) and their unrivalled success in HIV management. Initial unequivocal evidence came to light that to introduce antiretroviral therapy (ART) at CD4 levels of 350 - 500 cells × 109/L in all adults, including pregnant women is beneficial for mortality and morbidity outcomes [2,3]. It follows naturally that the earlier the initiation of ART takes place in pregnancy, the lower is the risk of HIV transmission to the infant. Due to earlier ART initiation the proportion of pregnant women living with HIV in South Africa on ART increased from 83% in 2009 to 87% in 2012 [4]. It is suggested that 10% of neonates who have HIV infection contract it in utero, 60% are infected peri- or intra-partum, while 30% of infants acquire HIV postnatally [5,6]
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