Abstract
A research study was conducted with the aim to investigate the frequency of Hepatitis B Virus positivity in the general population of district Lakki Marwat. Blood samples were collected from 2000 individuals in various hospitals and diagnostic/ medical laboratories of the study area. All the blood samples were evaluated for HBV by Liver function tests (LFTs), Immuno-chromatographic tests (ICT) and PCR. Among the total, 108 blood samples were found positive for the virus with a prevalence rate of 5.4%. A higher prevalence rate (4.15%) was found in males as compare to 1.25% in females. Among the total HBV positive samples 83 (76.85%) were male (from 4 years to 75 years) and 25 (23.19%) were female (from 5 years to 60 years). The HBV positive data was also analyzed for various age groups i.e. 1-15 years, 16-30 years, 31-45 years, 46-60 years and above 60 years. It was found that disease prevails more in males than in females and is predominant in the age group 16-30 (57%), followed by age groups 31-45 (23%), 1-15 (10.18%), 46-60 (7%) and >60 (3%) respectively. Various risk factors were found involved in the spread of HBV in the study area like medical injections (59.26%), dental procedures by medical quacks (12.04%), hair dressing and shaving salons/ barber shops (11.11%), transfusion of blood and blood based products (5.56%), mother to children transmission (3.70%), occupational risk groups (2.78%), sexual transmission (2.78%), tattooing (0.92%), circumcision (0.92%) and shared injection by drug abuser (0.92%). Keywords: Frequency; HBV; ICT; PCR; Risk factors http://dx.doi.org/10.19045/bspab.2020.90267
Highlights
A research study was conducted with the aim to investigate the frequency of Hepatitis B Virus positivity in the general population of district Lakki Marwat
The current study revealed a higher Hepatitis B Virus (HBV)
In the present study the highest prevalence of disease was observed in age groups 16-30, which coincides the work of many scientists [29, 32, 34, 35]
Summary
Hepatitis which literally means specificity and epidemiology. Hepatitis A inflammation of the liver; is caused by six and hepatitis E viruses cause water and food different types of viruses, which are borne diseases while hepatitis B, hepatitis hepatitis A virus (HAV), hepatitis B virus. To know about the risk factors the patients above age 16 years were investigated that “what would be the possible reason to get this disease in their view?” The above said question was asked from the parents of kids (≤ 15 years of age) Their responses were analyzed and it was found that medical injections (59.26%), dental procedures (12.04%), hair dressing & shaving in barber shops (11.11%) and transfusion of blood & blood based products (5.56%) are the major risk factors of HBV spread in the study area while mother to children transmission (3.07%), occupational risk groups (2.78%), sexual transmission (2.78%), Circumcision (0.92%), Tattooing (0.92%) and injecting abused drugs (0.92%) are least significant risk factors (Table 3)
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