Abstract

1. 1. Glycine transhydroxymethylase and threonine aldolase function in the formation of serine in Tetrahymena pyriformis S. 2. 2. Both the phosphorylated and non-phosphorylated pathways of serine biosynthesis from 3-phosphoglycerate are also operative. 3. 3. Tricarboxylic acid cycle intermediates also serve as serine precursors in this organism. 4. 4. Pyruvate, short chain fatty acids, and at low concentrations, α-ketoglutarate, appear to serve as energy sources for serine incorporation.

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