SERIE DE CASOS: MIELOMA MÚLTIPLE DIFERENCIACIÓN CLÍNICA, DIAGNOSTICA Y TERAPÉUTICAS EN TIEMPOS DE PANDEMIA 2020.

Abstract

Introduction Multiple myeloma is a neoplasm caused by the proliferation of a clone of plasma cells that in most cases produce a monoclonal protein. Due to its decreased incidence of 4-5 cases per 100,000 inhabitants. Case description The General Hospital San Francisco Quito-Ecuador was diagnosed during this time of pandemic: three cases of Multiple Myeloma, with diverse presentation both in clinical manifestations, laboratories and radiographs, taking us to carry out a series of clinical cases with the objective of differentiating the type of clinic, diagnosis and therapy in times of pandemic in 2020. Finding different diagnoses at admission such as acute coronary syndrome, acute pancreatitis and heart failure, which were later discarded and evidenced in general bone pain, hyperamylasemia and hyperglobulinemia, with image changes both in bone punches and pathological fractures that led to the suspicion of Multiple Myeloma and performance of a medullogram for definitive diagnosis. The subspecialty treatment will run without complications. Conclusion The main characteristics are pathological fractures that can present in the form of acute or chronic pain, as well as related to other pathologies; and since the rest of the clinical manifestations mentioned in the literature were not present. It is also worth mentioning that hyperamylasemia was a factor found in our cases that future studies could be related as a prognostic factor and mortality in multiple myeloma