Sequential ERCP and laparoscopy for acute biliary pancreatitis

Abstract

Objective To investigate the efficacy of sequential ERCP and laparoscopy for acute biliary pancreatitis （ABP）. Methods A total of 80 patients with ABP were randomly divided into 2 groups to receive sequential ERCP and laparoscopy （ observation group, n = 40） or traditional surgery （ control group, n = 40）. Clinical data including abdominal pain relief time, recovery time of white blood cell, blood amylase and liver function, hospital stay, complication rate and mortality were analyzed. Results ERCP failed in 1 patient in observation group , and the remaining 39 patients （ 97. 5% ） were recruited into the study. There were significant differences between 2 groups in regarding of abdominal pain relief time （ 7. 7 ± 2. 7 d vs. 11.4 ＋3.7 d）, recovery time of white blood cell （9. 7 ± 2. 6 d vs. 13.3 ± 3.9 d）, blood amylase （ 8.2 ± 2.1 dvs. 12.5±3.3 d）, liver function （12.5±5.1 dvs. 21.3±6.5 d）, hospital stay （16.1 ±5.1 dvs. 23. 3 ±7. 6 d） and rate of complication （ 12. 8% vs. 30. 0% ）. There was no significant difference in morbidity between 2 groups （5. 1% vs. 7. 5% ）. Conclusion Sequential ERCP and laparoscopy is effective for ABP. Key words: Pancreatitis ; Biliary tract ; Acute disease ; Duodenoscopes ; Cbolecystectomy, laparoscopic