Abstract
Sequential Contraction Compression Devices Reduce Leg Circumference in Patients with Chronic Venous Insufficiency
Highlights
The more advanced stages of venous disease, Chronic Venous Insufficiency (CVI) (C3-C6), appear to affect about 5% of the population, with the prevalence of the end stages of CVI estimated at 1-2% [1]
The mechanism of venous leg ulcer formation involves a sequence of pathophysiologic steps that are thought to include [1] reduction in venous outflow due to venous obstruction and/or reflux, [2] persistent venous hypertension, and subsequent increased capillary filtration and interstitial fluid load [3]
Excess interstitial fluid is effectively removed by the lymphatics, but if the fluid load overwhelms the lymphatic capacity or if the lymphatics are defective, the accumulation of interstitial fluid, macromolecules, and cytokines lead to edema (CEAP C 3 ), breakdown of subcutaneous tissue (C 4A,B ), and formation of ulcers (C 6 ) [2,3]
Summary
The more advanced stages of venous disease, Chronic Venous Insufficiency (CVI) (C3-C6), appear to affect about 5% of the population, with the prevalence of the end stages of CVI (active and healed venous ulcers, C5+C6) estimated at 1-2% [1]. Compression of the leg is the mainstay of therapy in patients who have CVI and is based on the understanding that gradient compression helps to relieve symptoms and to improve venous function. A variety of compression devices are available, including elastic bandages, gradient compression stockings, and Intermittent Pneumatic Compression (IPC) Devices. This is because it has been shown that continued use of compression therapy leads to improvement in the symptoms and on signs of CVI and documentation of changes in venous blood flow velocities [4,5,6]. There are many problems with existing compression therapies; the most prominent being patient compliance [7]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
