Abstract

A patient with fever, and haemorrhagic symptoms was admitted to a hospital in Glasgow on 2 October 2012. Since he had returned from Afghanistan, serum samples were sent for diagnosis at the Rare and Imported Pathogens Laboratory, where a real-time reverse transcriptase-PCR diagnosis of Crimean – Congo haemorrhagic fever was made within 3 hrs after receipt of the sample. Hereafter the patient was transferred to a high-security infectious diseases unit in London but died on 6 October.

Highlights

  • A patient with fever, and haemorrhagic symptoms was admitted to a hospital in Glasgow on 2 October 2012

  • Since he had returned from Afghanistan, serum samples were sent for diagnosis at the Rare and Imported Pathogens Laboratory, where a real-time reverse transcriptase-PCR diagnosis of Crimean – Congo haemorrhagic fever was made within 3hrs after receipt of the sample

  • On 3 October 2012, a serum sample was couriered to the Health Protection Agency’s (HPA) Microbiology Services Division (MSD), Porton Down which tested PCR-positive for Crimean – Congo haemorrhagic fever (CCHF) in an assay developed in-house following collaborative work between HPA and Central Asian colleagues

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Summary

Rapid communications

Sequencing and phylogenetic characterisation of a fatal Crimean – Congo haemorrhagic fever case imported into the United Kingdom, October 2012. A patient with fever, and haemorrhagic symptoms was admitted to a hospital in Glasgow on 2 October 2012. Since he had returned from Afghanistan, serum samples were sent for diagnosis at the Rare and Imported Pathogens Laboratory, where a real-time reverse transcriptase-PCR diagnosis of Crimean – Congo haemorrhagic fever was made within 3hrs after receipt of the sample. Hereafter the patient was transferred to a high-security infectious diseases unit in London but died on 6 October

Case report
Laboratory investigations
Control measures
Discussion
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