Abstract
The mass-analysed ion kinetic energy spectrum of isomeric dinucleotides having dTpdU and dUpdT structure is characterized by the preferred elimination of the pyrimidine base linked to the 5' end deoxyribose unit. Similar results have been obtained with differently substituted dimers such as dCpdT and DMTdTp(S)dU. The observed selectivity in the glycosidic bond dissociation provides a straightforward criterion for the sequencing of the sampled species.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.