Abstract
The septate junctions of the gastrodermis of the hydromedusa, Phialidium gregarium, are composed of septa (80 Å thick) which bridge the gap (130 Å) between the outer leaflets of the plasma membranes of adjacent cells. The septa are parallel walls, presumably continuous around the cells, and en face show a periodicity of 110 Å. Examination of material fixed in a ruthenium red-containing mixture shows that this dye penetrates the interseptal compartments and illucidates the finer structure of the septa. A model of an interpretation of the three-dimensional structure of the junction is presented and relevance of the results to current theories of cell communication is discussed.
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