Sepsis associated acute kidney injury in pediatric intensive care unit.

Abstract

We aimed to compare the acute kidney injury (AKI) incidence in pediatric septic shock patients according to the three different classifications. We analyzed retrospectively 52 patients with severe sepsis between January 2019 and December 2019. While 21 patients have been diagnosed with SA-AKI according to the pRIFLE criteria, 20 children have been diagnosed according to the AKIN criteria, and 21 children have been diagnosed according to the KDIGO criteria. Older age, lower platelet count were determined as independently risk factor for SA-AKI. Older age and higher PRISM score were associated with mortality. According to Canonical correlation coefficients, pRIFLE is the most successful classification to distinguish AKI state. The canonical correlation coefficients for pRIFLE, KDIGO, and AKIN were 0.817, 0.648, and 0.615, respectively. Although AKI incidence was similar between the three classifications, pRIFLE was the most successful classification to distinguish AKI state.