Abstract
Sepsis and the killer platelets Dermot Cox BSc, PG Dip Ed, PhD, Pharmacology Lead from the School of Pharmacy and Biomolecular Sciences – RCSI University of Medicine & Health Sciences, discusses sepsis and the killer platelets. Sepsis is defined as “life-threatening organ dysfunction caused by a dysregulated host response to infection” (1) (Sepsis 3) and is typically diagnosed using the Sequential Organ Failure Assessment (SOFA) score. While sepsis typically arises in response to a bacterial infection, surprisingly, around 40% of cases are culture negative. The cause of culture negative sepsis is unclear but could be due to bacterial species that are difficult to grow in the lab.
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