Sepsis and Dialysis Disequilibrium Syndrome

Abstract

Dialysis disequilibrium syndrome (DDS) is a central nervous system disorder, usually occurs in patients during hemodialysis (HD) or within 24 hours of HD. DDS was first described by Kennedy et al. in 1962. 11 If a critically ill patient on HD develops severe sepsis and septic shock with multiple organ failure (MOF), the adverse effect of HD on the brain is likely to be amplified, which may predispose to the DDS.