Abstract
From a European cohort 55 patients with early stage Lyme-neuroborreliosis were tested with somatosensory evoked potentials (SEPs) by stimulating the tibial nerve SEP and/or the median nerve SEP. The tibial SEP seems to be more sensitive in the detection of nerve lesions in clinically symptomatic limbs (67 % versus median SEP: 57 %). With both methodes it was possible to unmask lesions in clinically asymptomatic nerves (tibial SEP: 38 %, median SEP: 30 %). In 16 % of all SEPs we found a combination of lesions in the peripheral and central nervous system, which seems to be specific for Lyme-neuroborreliosis and may help in diagnosing the disease. In our study pathological findings in SEPs proved to be reversible what is of differential diagnostic meaning.
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