Abstract
SummaryMagnesium pemoline (20 mg/kg, ip) was found to enhance the acquisition and retention of a double-T maze in male Swiss-Webster mice when administered 25 min prior to training or from 1 to 180 min posttrial. The general stimulant action of magnesium pemoline was completely abolished by pretreatment with chlordiazepoxide (15 mg/kg, sc), although the mice still showed enhanced memory of the avoidance task. These data suggest that the nonspecific arousal associated with magnesium pemoline is not responsible for the demonstrated effects upon avoidance learning and memory.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
