Abstract
The effect of sandwich configurations of paired ultrafiltration membranes on the transmission and rejection of proteins were evaluated using various sandwich arrangements. Data is presented for the fractionation of BSA and myoglobin, and for that of lysozyme and myoglobin. Two membranes were sandwiched together in several different configurations without spacer. The sandwich configurations were known as SS-sandwich, BS-sandwich, BB-sandwich and SB-sandwich, where S indicates that the skin layer faces the feed and B indicates that the support layer faces towards the feed. The result of single membrane transmission was compared with the transmission of the various sandwich arrangements. Interestingly not having a skin layer on top and in contact with the feed (as in BS and BB sandwich configurations) was useful for enhancing protein transmission whilst SS and SB configurations can be used to increase protein rejection. For the separation of lysozyme and myoglobin, a selectivity value of 9 was found for S, SS and SB configurations The effect of sandwich membranes varies not only with MWCO but also, to a small extent, with different types of membrane material. For example, the transmission of both proteins using single membranes is comparatively higher than the sandwich membrane for RC and PES membranes, but this was not found to be so for YM membranes.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
