Abstract
A method of microparticle separation from larger volumes of suspension is proposed. A piezoelectric cylinder is selected as an ultrasonic wave actuator, the diameter and length of which the volume of the suspension to be purified depends. Numerically and experimentally, it is demonstrated that the low-level pressure field nodal circles of ultrasonic radiation standing waves concentrate microparticles at different velocities depending on the fluid viscosity. Numerical mathematical modeling has allowed us to identify the basic dynamic characteristics of the piezoelectric actuator to ensure a more effective process of microparticle separation. An important feature of the proposed method is that the ultrasonic radiation stresses that are directly applicable to cell membranes are inadequate to cause them damage.
Highlights
Acoustic standing wave technology creates new opportunities to improve advanced particle and cell separating systems
The boundary of the acoustic fluid pressure domain was excited by normal acceleration of a piezoelectric actuator cylinder element
It was found that the distribution of both biological and water suspension particles in the acoustic pressure field is the same, yet the velocity of particle convergence to the low-level pressure field is different
Summary
Acoustic standing wave technology creates new opportunities to improve advanced particle and cell separating systems. The influence of ultrasonic waves on the diffracting phase is interesting itself as one of the fundamental physics effects of ultrasound. Apart from the acoustic radiation forces, Rayleigh streaming flows are normally detected in acoustic-fluidic manipulation and sorting devices [2]. Several experimental studies were performed [3] to examine the ways bio-particles can be manipulated using acoustics. For the evaluation of the effectiveness of this technology, digital particle image velocimetry is an optical method of flow visualization, which is described in terms of linear system theory [4,5], and the conditions for correlation analysis as a valid interrogation method are determined
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