Abstract
The possibilities of separating various aromatic sulphonic acids used as intermediates in production of synthetic dyes by reversed-phase high-performance liquid chromatography (HPLC) and capillary zone electrophoresis (CZE) were studied. Isomeric naphthalene mono- to tetrasulphonic acids are best separated by HPLC with aqueous-methanolic mobile phases containing sodium sulphate. A high content of bonded hydrocarbon moieties is essential for successful separation. Components of technological samples of 4,4'-dinitrostilbene-2,2'-disulphonic acid can also be successfully separated using this technique, but the separation is very sensitive to the concentration of methanol in the mobile phase. Various aromatic aminosulphonic acids (letter acids) in technological samples can be separated by ion-pair reversed-phase chromatography with mobile phases containing tetrabutylammonium ions, but a better separation is possible using capillary zone electrophoresis with working electrolytes containing β-cyclodextrin. The opposite applies to the separation of naphthalenesulphonic acids and dinitrostilbenedisulphonic acid isomers, so that the HPLC and CZE are complementary to each other. Both HPLC and CZE techniques are suitable for the quantitative analysis of technical products containing aromatic sulphonic acids.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
