Abstract

ObjectivesCurrently, no standardized method is available to predict success rate after percutaneous nephrolithotomy. We devised and validated the Seoul National University Renal Stone Complexity (S-ReSC) scoring system for predicting the stone-free rate after single-tract percutaneous nephrolithotomy (sPCNL).Patients and MethodsThe data of 155 consecutive patients who underwent sPCNL were retrospectively analyzed. Preoperative computed tomography images were reviewed. The S-ReSC score was assigned from 1 to 9 based on the number of sites involved in the renal pelvis (#1), superior and inferior major calyceal groups (#2–3), and anterior and posterior minor calyceal groups of the superior (#4–5), middle (#6–7), and inferior calyx (#8–9). The inter- and intra-observer agreements were accessed using the weighted kappa (κ). The stone-free rate and complication rate were evaluated according to the S-ReSC score. The predictive accuracy of the S-ReSC score was assessed using the area under the receiver operating characteristic curve (AUC).ResultsThe overall SFR was 72.3%. The mean S-ReSC score was 3.15±2.1. The weighted kappas for the inter- and intra-observer agreements were 0.832 and 0.982, respectively. The SFRs in low (1 and 2), medium (3 and 4), and high (5 or higher) S-ReSC scores were 96.0%, 69.0%, and 28.9%, respectively (p<0.001). The predictive accuracy was very high (AUC 0.860). After adjusting for other variables, the S-ReSC score was still a significant predictor of the SFR by multiple logistic regression. The complication rates were increased to low (18.7%), medium (28.6%), and high (34.2%) (p = 0.166).ConclusionsThe S-ReSC scoring system is easy to use and reproducible. This score accurately predicts the stone-free rate after sPCNL. Furthermore, this score represents the complexity of surgery.

Highlights

  • The incidence of urolithiasis is approximately 5% to 10% in the general population, and 30% of the surgical workload is related to urinary stone treatment in an active urologic department [1,2]

  • We evaluated the ability of the Seoul National University Renal Stone Complexity (S-ReSC) scoring system to predict the stone-free rate (SFR) and represent the surgical difficulty of single-tract percutaneous nephrolithotomy (PCNL) Institutional Review Board (IRB)

  • Ethics Statement This study was approved by the Institutional Review Board (IRB) of Seoul National University Bundang Hospital (Seongnam, Republic of Korea)

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Summary

Introduction

Large renal stones should be actively treated, except in patients who are otherwise too ill to tolerate stone removal. Percutaneous nephrolithotomy (PCNL) is a standard treatment for patients with large renal stones [3,4], because it has been demonstrated to have the highest stone-free rate (SFR) [3]. It does not result in a 100% SFR. The recently published Clinical Research Office of the Endourological Society (CROES) PCNL global study reported an SFR of 75.5% and a complication rate of 20.5% [5]

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