Abstract
Metastatic breast cancer is essentially an incurable disease. However, recent advances have resulted in a significant improvement of overall survival. The SEOM guidelines are intended to make evidence-based recommendations on how to manage patients with metastatic breast cancer to achieve the best patient outcomes based on a rational use of the currently available therapies. To assign a level of certainty and a grade of recommendation the United States Preventive Services Task Force guidelines methodology was selected as reference.
Highlights
Metastatic breast cancer is essentially an incurable disease
To assign a level of certainty and a grade of recommendation the United States Preventive Services Task Force guidelines methodology was selected as reference
To assign a level of certainty and a grade of recommendation to the different statements described in the clinical guidelines, the United States Preventive Services Task Force (USPSTF) guidelines methodology was selected as reference [1] (Table 1)
Summary
Metastatic breast cancer is essentially an incurable disease. recent advances in the medical treatment of patients with some of the most frequent subtypes ( the luminal and HER2 subtypes) have resulted in a significant improvement of the median overall survival (OS) of these patients; median OS figures of around 5 years have been reported in the most recent randomized trials in patients with these subtypes. This guide is intended to make evidence-based recommendations on how to manage patients with metastatic breast cancer to achieve the best patient outcomes by means of a rational use of the currently available therapies
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