Sentinel node biopsy in clinical stage I testicular cancer enables early detection of occult metastatic disease.

Abstract

ObjectivesTo report the long‐term results of the sentinel node (SN) approach in patients with clinical stage I testicular tumours in our facility.Patients and MethodsWe conducted an analysis of 27 consecutive patients suspected of clinical stage I testicular germ cell tumour (TGCT) and treated with an SN procedure at our tertiary referral centre. SNs were identified using lymphoscintigraphy with or without single‐photo‐emission computed tomography with CT (SPECT/CT). Patients underwent laparoscopic retroperitoneal SN excision with inguinal orchiectomy. Patients with a tumour‐positive SN underwent adjuvant treatment. Follow‐up was conducted according to then‐current guidelines.ResultsIn two patients, no SNs were visualized on scintigraphy. In the remaining 25 patients, a median (range) of 3 (1–4) SNs per patient were removed. Two patients showed no malignancy on histopathological examination of the testis. Of the 23 patients diagnosed with TGCT (16 seminomas, seven non‐seminomas), three (13.0%) had occult metastatic disease. All 23 patients were without evidence of disease at a median (range) follow‐up of 63.9 (29.0–143.4) months.ConclusionThe SN procedure allows early identification of patients with occult metastatic disease in clinical stage I TGCT, enabling early treatment.