Abstract
The rheological conditions which operate during spreading of topical preparations on the skin were investigated for a series of lipophilic preparations ranging from stiff semisolids to mobile liquids. Rates of shear were found to vary from approximately 400 to 2500 sec.−1 depending on the consistency of the preparation being spread; a rheological master curve was determined. Three types of scaling procedures (ordinal, preference, and ratio scaling), employed to investigate the ability of a panel to differentiate levels of the textural parameter spreadability, were found to be of similar efficiency. The data derived were used to indicate a method for determining instrumental rheological conditions for use in routine industrial control procedures and a spreadability screening test for application during innovative work prior to field trials.
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