Sensory nerve conduction study in patient of thyroid dysfunction in central India

Abstract

Introduction: Hypothyroidism is a endocrine disorder which results in neurological dysfunction. It also affects brain, peripheral nerves and muscular system. The neurologic manifestations, which may be noted incidently, occur in conjunction with the systemic features of the disease. Peripheral neuropathy occurs early in hypothyroidism and its detection is necessary for early diagnosis and treatment. Study aimed to know the sensory nerve conduction in patients of hypothyroidism and to compare sensory nerve conduction parameters in patients of hypothyroidism with normal healthy controls. Materials and Methods: Comparative study. Study Design: Total 100 subjects were taken in the study in the age group of 18–66 years. Out of 100 subjects 50 were diagnosed thyroid dysfunction patient and 50 subjects were healthy individual. Informed written consent was taken from all the subjects. Nerve conduction study consists of sensory nerve conduction study of Median, Ulnar and Sural nerves. In the department of Physiology. Electrophysiological parameters such as Sensory Nerve Action Potential amplitude and conduction velocity were evaluated. Results: It was found that sensory nerve action potential amplitude and conduction velocity were significantly reduced in median and ulnar nerves in cases as compared to controls. Conclusion: Nerve conduction study very effective test for early diagnosis of peripheral neuropathy in thyroid dysfunction.