Abstract

House dust mites are the leading cause of respiratory allergy, and atopic reactivity to their products is one of the most common causes of allergy worldwide. To date, more than 30 groups of allergens have been identified in house dust mites, of which the major allergens are considered to be in groups 1, 2 and 23. Another clinically relevant group appears to be group 10, due to its ability to induce cross-reactivity with other invertebrates. Accurate molecular diagnosis of allergy to house dust mites can highlight individual sensitization profiles, which can be used to determine the primary source of sensitization, to assess the risk of severe reactions and cross-reactions, and to optimize the results of allergen immunotherapy.

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