Abstract
At present, sensitization to airborne allergens in domestic animals is absolutely rightly considered one of the key risk factors for the development of allergic rhinitis and bronchial asthma, as well as largely determines the development of severe forms of atopic dermatitis and respiratory allergosis. Of particularimportance isthe fact that, unlike othertriggers, the elimination of allergensin domestic animals is often associated with internal resistance from patients. The article presents the current data on the prevalence of sensitization, the properties and clinical significance of the main allergens of cats and dogs, outlines approaches to conducting elimination activities.
Highlights
Veltischev Research and Clinical Institute for Pediatrics of the Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation, Moscow
Of particular importance is the fact that, unlike other triggers, the elimination of allergens in domestic animals is often associated with internal resistance from patients
The article presents the current data on the prevalence of sensitization, the properties and clinical significance of the main allergens of cats and dogs, outlines approaches to conducting elimination activities
Summary
Обусловливающие формирование IgE-опосредованной сенсибилизации и в дальнейшем развитие клинических проявлений аллергии к ингаляционным аллергенам домашних животных, условно можно разделить на три группы: характеристики субъекта, особенности экспозиции аллергена, дополнительные воздействия. Сенсибилизация к аллергенам домашних животных сенсибилизации к Fel d 1, Fel d 4, но не к Fel d 2 [5]. Что наличие sIgE к аллергенам традиционных питомцев (кошка, собака) резко повышает вероятность развития сенсибилизации к аллергенам других млекопитающих.
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