Abstract
Sensitization state of 119 patients of end-stage renal disease registered for live related donor transplant was assessed by determining the panel reactive antibody (PRA) status and the donor-specific crossmatch positivity. Eighty one patients (69.1%) showed no PRA, whereas 27 (22.6%) had PRA less than 10% and the remaining 11 patients (9.2%) displayed PRA more than 10%. The lower level of sensitization was related to the short dialysis period, less number of blood transfusions, fewer female patiente, and lesser number of retransplants. Cross-match positive patients were in the higher PRA group (range 32-68%) as compared to 0-24% PRA in cross-match negative group.
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