Abstract

The aim of this study was to determine the prevalence of sensitization to common allergens in children with allergic rhinitis (AR) living in Qingdao, China. We conducted a retrospective analysis for AR cases, who underwent skin prick tests (SPT) in Qingdao. A total of 2841 children with AR qualified for the inclusion criteria (Age 3–5 years: 1500 children; Age 6–12 years: 1341 children). The most common inhaled allergens to which the AR children were sensitive were Dermatophagoides pteronyssinus (69.3%), Dermatophagoides farinae (66.2%) and mould 1 (Penicillium notatum 38.9%); while the corresponding ingested allergens were mussel (39.2%), shrimp (36.3%) and carp (36.5%). The prevalence of sensitization to inhaled allergens and food allergens was higher in children >6 years of age as compared to that in children 3–5 years of age (all p < 0.05). Children >6 years old were more sensitive to dust mite as compared to children 3–5 years old (p < 0.05). Sensitization to dust mite was more common in males than in females (p = 0.05). In this study, Dermatophagoides pteronyssinus and Dermatophagoides farinae were the most common allergens causing AR in children in Qingdao, China. Older children with AR, particularly males, were found to be more sensitive to dust mite.

Highlights

  • Allergic rhinitis (AR) is a common allergic disorder involving the respiratory system in both adults and children

  • The percentage of positive skin test to various allergens was calculated as positive rate (%)

  • The study population comprised of 2841 children with AR, with or without asthma (1732 male, females; average age 6.03 ± 2.81 years)

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Summary

Introduction

Allergic rhinitis (AR) is a common allergic disorder involving the respiratory system in both adults and children. It is characterized by inflammation of nasal mucosa caused by an immunoglobulin E (IgE)-mediated immune reaction to specific allergens [1,2]. Clinical manifestations of AR include nasal congestion, nasal itching, nasal catarrh, sneezing, and other allergic symptoms such as ocular pruritis, redness of eyes and/or lacrimation. It seriously affects the study, work efficiency and quality of life. Allergic rhinitis is a global public health problem, and can exert adverse impact on patient’s quality of life.

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