Abstract

Urinary Tract Infections (UTI) constitute serious health problems affecting all ages and sexes. The microorganisms implicated in urinary tract infections from four different hospitals in Makurdi Metropolis, Nigeria were investigated. Two hundred midstream urine samples were collected from both male and female patients for analysis by Kirby Bauer’s method following the definition of the National Committee of Clinical Laboratory Standards. The microorganisms present in the urine samples that were identified to cause UTI in four hospitals within Makurdi Metropolis included Escherichia coli (43.8%), Staphylococcus aureus (23.9%), Klebsiella spp (10.74%), Streptococcus pyogenes (9.09%), Pseudomonas aeruginosa (8.26%) and Proteus species (4.13%). The result showed that 39.5% of the urine samples collected had no microorganism. The isolates in female patients were higher (77%) compared to the male patients (44%). Antimicrobial drugs such as gentamicin and erythromycin tested on the isolated microorganisms showed higher efficacy to all isolates, while streptomycin, tetracycline and ampicillin showed lower efficacy to the probable isolates. This research showed that Escherichia coli are the major cause of UTI.

Highlights

  • Urinary Tract system is composed of the kidneys, ureters, bladder and urethra

  • Objectives of the Study The aim of the study was to isolate and identify the microorganisms associated with urinary tract infection (UTI) and to determine their antimicrobial susceptibility patterns as well as the rate of Urinary tract infection (UTI) infection among patients in Makurdi metropolis

  • The microorganisms causing urinary tract infections in both male and female patients attending four different hospitals in Makurdi town revealed that 60.5% showed positive isolates while 39.5% of the urine samples had no isolates

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Summary

Introduction

Urinary Tract system is composed of the kidneys, ureters, bladder and urethra (and prostrate gland in males). Its main function is excretion of the urine. The urinary tract consists of various organs of the body that produce, store and get rid of urine. The tract just like any other system can be infected and an infection of any part of the system can spread to the whole system [14]. Urinary tract infection (UTI) is defined as an infection in any part of the urinary system accompanied by symptoms. They are severe health problems which affect 150 million people each year worldwide [21;3]

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