Abstract
Transplantable rat tumours (sarcoma M-1, sarcoma 45, alveolar liver cancer PC-1 and Pliss' lymphosarcoma) were used to study chlorin e 6 accumulation in tumours and its photodynamic effect. Tumours were irradiated by krypton ion laser light (647 and 676 nm; 90 J cm −2) 15 min and 24 h after chlorin e 6 injection at doses of 5 and 10 mg kg −1. The relationship between some morphological peculiarities of these tumour strains, photosensitizer accumulation in tumours and their response to the photodynamic treatment is discussed.
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Schedule a callMore From: Journal of Photochemistry & Photobiology, B: Biology
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