SENSITIVITY AND SPECIFICITY OF THE OPTOS OPTOMAP FOR DETECTING PERIPHERAL RETINAL LESIONS

Abstract

To compare the sensitivity and specificity of the Optomap Panoramic200 wide-field confocal scanning laser imaging system for detecting peripheral retinal lesions. Optomap images were obtained in patients with known retinal pathology. Two masked retinal specialists evaluated Optomap images to identify lesions requiring referral to a retinal specialist. Their performance was compared to gold standard examination with scleral indentation performed by a retinal specialist. Sensitivity was calculated overall and again for lesions that were found on clinical examination to require treatment. These sensitivities were calculated separately for lesions posterior and anterior to the equator. Specificity was calculated from fellow eyes that were found to have no pathology on clinical examination. For retinal lesions posterior to the equator, sensitivity was 74% (95% confidence interval [95% CI] 61%-87%) overall for all lesions and 76% (95% CI 59%-93%) for lesions requiring treatment. For anterior lesions, sensitivity was 45% (95% CI 28%-62%) overall and 36% (95% CI 14%-58%) for treatable lesions. Specificity was 85% (95% CI 63%-100%). The Optomap showed high specificity and moderate sensitivity for lesions posterior to the equator and low sensitivity for lesions anterior to the equator.