Sensitivity and Resistivity Pattern of some commonly used Antibiotics against Urinary Tract Infection (UTI) among elderly individuals from Garhwal Region of Uttarakhand, India

Abstract

Urinary Tract Infection is a very common kind of microbial infection (mainly bacterial) that affects all the age groups. A high UTI infection rate has been reported in 51 and above aged population beside it’s highly prevalent in sexually active population. In recent times most of the commonly used antibiotics has reported being less effective against UTI. In this light a retrospective study was designed to understand the resistivity and sensitivity pattern of bacterial population against commonly used antibiotics in 51 plus population of Garhwal region. Urine samples from individuals were collected in sterile bottles. Bacterial cultures from these samples were obtained, pure cultures were isolated and identified using their characteristic biochemical tests. Resistivity and sensitivity pattern of antibiotics were assessed by agar well method. A high infection rate reported in males as compared to females. E. coli was found main infective agent in most of the samples followed by S. aureus and CoNS. High resistance level was observed against most of the antibiotics generally used while meager of such antibiotics found sensitive to isolates. The high resistivity shown by bacterial population to antibiotic can be attributed to the irrational use and this highlights the need of developing novel antibiotics. The study provides a baseline data for the UTI sensitive elderly population of Garhwal region. This will also help the state health department in making strategies to contain the infection among elderly people which sometimes becomes life-threatening in the remote hilly areas of this region.