Abstract
A novel voltage interrogation method using electro-optically tunable waveguide-coupled surface plasmon resonance sensors is demonstrated. Before measurements, we use a bicell photodetector to detect the reflectance from the sensor and take the differential signal from the photodetector as the resonance condition. For different analytes, by scanning the DC voltage on the waveguide layer of the sensor chip, the resonance condition can be maintained the same. Under this condition, we record the values of this voltage, namely the resonant voltage. Theoretical calculations and experimental results show the resonant voltage has a highly linear and sensitive response to analyte's refractive index. This method is simple in configuration, and complicated signal processing algorithms can be avoided.
Highlights
Surface plasmon resonance (SPR) sensors have been widely explored as a label-free, highly sensitive and real time tool in both fundamental and applied biochemistry as well as in other areas [1]
To further simplify the data processing method and apparatus employed in the SPR sensing, we propose and experimentally demonstrate a novel voltage interrogation method that can get the corresponding resonant voltages in scan of DC voltage applied on a tunable SPR sensor by keeping the resonance conditions the same for different analytes at a fixed wavelength
The reflectivity of WCSPR mode of the sensor is measured by the angular interrogation over a range of incident angles. 0.4 wt% glucose solution is used as the analyte
Summary
Surface plasmon resonance (SPR) sensors have been widely explored as a label-free, highly sensitive and real time tool in both fundamental and applied biochemistry as well as in other areas [1]. In SPR sensing systems, attenuated total reflection (ATR) is the most common configuration, in which the wave vector of TM-polarized light of a specific wavelength at an incident angle matches that of the surface plasmon wave (SPW) and the reflectance reaches minimum, producing a dip in the spectrum. Since the value of the derivative was zero at the resonant angle, simple linear fitting and zero-finding algorithms could be used to determine the angle This method simplifies the data processing methods used and realizes sensitivity similar to that of angular interrogation is possible. We will prove the feasibility of this interrogation method and demonstrate it experimentally
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