Sensitive and sustained imaging of intracellular microRNA in living cells by a high biocompatible liposomal vehicle introduced isothermal symmetric exponential amplification reaction.

Abstract

A high biocompatible liposomal vehicle was used to deliver enzymes and oligonucleotide substances of the isothermal symmetric exponential amplification reaction into living cells, allowing sensitive and sustained imaging of microRNA in living cells for more than 24 h without apoptosis.