Abstract

SENEX is a computer application in its fifth year of development focused on representation of molecular information, presentation of data, and reasoning with molecular information. It is written in a portable programming environment supported by Common Lisp, the Common Lisp Object System (CLOS), and the Common Lisp Interface Manager (CLIM). SENEX contains information about molecules, molecular events and disease processes, and provides tools for reasoning with and displaying this information in useful ways. This paper describes the architecture of SENEX and how that architecture facilitates development of a set a computer tools for education and research in molecular pathology. Several examples of how an individual might currently use SENEX to explore information related to the molecular basis of Alzheimer's disease are illustrated.

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