Abstract

A series of hybrid molecules 7–13 of boswellic acid (BA)/11-keto-β-boswellic acid (KBA) 1/2 with well-known anti-inflammatory drugs (i.e. aspirin, naproxen, ibuprofen and cinnamic acid) have been synthesized and evaluated for their anti-inflammatory and anti-arthritic activities. Two of hybrid compounds 8 and 11 bearing naproxen and BA/KBA unit have displayed promising anti-inflammatory and anti-arthritic activities than the standard drugs.

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