Seminoma e sertolioma em cão não criptorquida – relato de caso

Guilherme Mantuani Silva,Gabriela Maria Benedetti Vasques,Paulo Fernandes Marcusso,Beatriz Gasser,Juliana Evangelista Bezerril,Isaac Romani,Rodrigo Samuel De Toledo,Isabela Cristina De Oliveira

doi:10.21708/avb.2021.15.4.10155

Abstract

The most common testicular neoplasms in dogs are seminoma, leydigocytoma and sertolioma, affecting middle--aged and elderly dogs, where cryptorchidism is a predisposing factor, as well as some breeds. It can occur alone or, less fren-quently, concurrently, generally affecting the same testicle. This study aimed to report the case of a non-cryptorchid 14-year--old mixed breed dog diagnosed with seminoma and sertolioma, each in a testicle. The animal showed an increase in scrotal volume, with no changes in other clinical parameters on physical examination. On ultrasound examination, it was possible to observe alterations suggestive of neoplasia in both testicles and prostatic alteration suggestive of benign prostatic hyperplasia. Complementary blood count and biochemical tests were performed and, as treatment, orchiectomy was performed. Fragments were collected from both testicles and sent for histopathological examination. Microscopy of the left testicle showed the presence of round cells, multiple and evident nucleoli, cells in different phases of mitosis and binucleation, these changes being compa-tible with seminoma. In contrast, in the right testicle, spindle and elongated cells (pseudo-lobular) were observed, presence of long cytoplasmic projections with rounded ovoid nucleus, spindle cells and degeneration of seminiferous tubules, compatible with sertolioma. It was observed that physical examination associated with ultrasound was efficient to detect the presence of neoplasms, being validated by histopathological examination. Orchiectomy was an assertive treatment indicated for this case.

Highlights

Testicular neoplasms are the most common disorders in the reproductive tract of male dogs, corresponding to approximately 90% of the reports of reproductive neoplasms and representing the second most common location observed in the species
In view of the above, the present study aimed to report the case of a non-cryptorchid dog presenting bilateral testicular neoplasms
The occurrence of sertolioma and seminoma in a bilateral cryptorchid dog has been reported which the ultrasound examination revealed the right testicle with preserved dimensions, parenchyma suggestive of normality, the left testicle with enlarged dimensions, heterogeneous and vascularized parenchyma, suggestive of neoplasia and prostatic hyperplasia, with heterogeneous parenchyma and anechoic areas (COSTA, 2016)

Summary

INTRODUCTION

Testicular neoplasms are the most common disorders in the reproductive tract of male dogs, corresponding to approximately 90% of the reports of reproductive neoplasms and representing the second most common location observed in the species. It is observed that approximately 40% of dogs that develop testicular neoplasms present more than one type of testicular tumor (STAUT; ASSEF; CIRIO, 2007) It is not commonly reported in the literature the presence of different neoplasms affecting different testicles in a non-cryptorchid animal. The ultrasound evaluation of the abdominal cavity did not reveal any changes, except for the prostate, presenting regular contours, bilobed aspect, measuring approximately 4.40 cm in length and 2.54 cm in height in longitudinal plane, with slightly heterogeneous parenchyma with the presence of cysts, suggestive of benign prostatic hyperplasia as can be seen in (Figure 1). In the testicular ultrasound examination (Figure 2b) decreased dimensions were observed in the right testicle (length: 2.61 cm, width: 1.32 cm, depth: 5.37 cm), with slightly heterogeneous parenchyma, suggestive of nodules / neoplasia and regular testicular mediastinum. In the ultrasound (Figure 4) and radiographic exams, no significant alterations were found, except for the same prostatic alterations observed previously compatible with benign prostatic hyperplasia, a reduction in size was observed when compared to the previous exam, with the measurements being 2.20 cm in length and 1.68 cm in height in longitudinal plane

DISCUSSION

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CONCLUSION