Abstract
SummaryTransferrin levels were determined in the seminal plasma of 185 men classified according to diagnosis of infertility and also on the basis of normal or abnormal semen analysis. There was a wide overlap between concentrations of seminal plasma transferrin between normal controls and infertile patients in the various diagnostic groups. Mean seminal plasma transferrin levels in men with oligo-asthenozoospermia and azoospermia were lower than those in men with normal semen. There was a positive correlation between seminal plasma transferrin concentration and sperm density, and between seminal plasma transferrin level and sperm motility. A weak negative correlation was found between transferrin and fructose concentrations in the seminal plasma. Seminal plasma transferrin is not a useful marker for Sertoli cell or seminiferous tubular dysfunction. The estimation of this protein in the seminal plasma is not of diagnostic value in male infertility.
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