Semi-automatic detection and segmentation algorithm of saccular aneurysms in 2D cerebral DSA images

Abstract

ObjectiveTo detect and segment cerebral saccular aneurysms (CSAs) in 2D Digital Subtraction Angiography (DSA) images. Patients and methodsTen patients underwent Intra-arterial DSA procedures. Patients were injected with Iodine-containing radiopaque material. A scheme for semi-automatic detection and segmentation of intracranial aneurysms is proposed in this study. The algorithm consisted of three major image processing stages: image enhancement, image segmentation and image classification. Applied to the 2D Digital Subtraction Angiography (DSA) images, the algorithm was evaluated in 19 scene files to detect 10 CSAs. ResultsAneurysms were identified by the proposed detection and segmentation algorithm with 89.47% sensitivity and 80.95% positive predictive value (PPV) after executing the algorithm on 19 DSA images of 10 aneurysms. Results have been verified by specialized radiologists. However, 4 false positive aneurysms were detected when aneurysms’ location is at Anterior Communicating Artery (ACA). ConclusionThe suggested algorithm is a promising method for detection and segmentation of saccular aneurysms; it provides a diagnostic tool for CSAs.