Abstract
Stepwise multiple regression affirmed that cAFP and cBIL contributed to the variation in the peak serum bilirubin concentration, r = 0.504, P <0.0001. In this study they were the only cord blood substances found to associate with postnatal serum bilirubin concentrations. However, no significant correlation existed between them. The incidence of idiopathic NNJ in a local Chinese population reported in 1986 was 23.8% [3]. Assuming the same incidence today, the positive predictive value and the efficiency of using a combination of cAFP (at a cutoff concentration of 100 000 j.tg/L) and cBIL (at a cutoff concentration of 29 j.molIL) would be 52.3% and 77.7%, respectively. We conclude that a combination of cAFP and cBIL can be used as a predictive marker for the development of idiopathic NNJ. Our results also indicated that both liver immaturity and increased bilirubin production were associated with the development of hyperbilirubinemia in newborn infants.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
