Abstract

The application of optical diffuse reflectance spectroscopy is impeded by the lack of exact analytical solution. Based on the results of the Monte Carlo simulation, a semi-empirical analytical expression is developed for diffuse reflectance from homogeneous spherical turbid media measured via small diameter detectors. It is valid over the typical optical property ranges for low absorption biological tissues. This solution is characterized by its simplicity and accuracy. The inversion of optical parameters of turbid media is performed using this solution. The reduced scattering coefficient can be inversely deduced from the diffuse reflectance measured via probes with various radii.

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