Semantic Sparse Representation of Disease Patterns

Abstract

Semantic Sparse Representation of Disease PatternsSparse data representation is discussed in a context of useful fundamentals led to semantic content description and extraction of information. Disease patterns as semantic information extracted from medical images were underlined because of discussed application of computer-aided diagnosis. Compressive sensing rules were adjusted to the requirements of diagnostic pattern recognition. Proposed methodology of sparse disease patterns considers accuracy of sparse representation to estimate target content for detailed analysis. Semantics of sparse representation were modeled by morphological content analysis. Subtle or hidden components were extracted and displayed to increase information completeness. Usefulness of sparsity was verified for computer-aided diagnosis of stroke based on brain CT scans. Implemented method was based on selective and sparse representation of subtle hypodensity to improve diagnosis. Visual expression of disease signatures was fixed to radiologist requirements, domain knowledge and experimental analysis issues. Diagnosis assistance suitability was proven by experimental subjective rating and automatic recognition.