Abstract

Calcific aortic stenosis is a slowly progressing disease with a large accumulation of calcium minerals. Several studies have been reported in the literature to investigate structural defects in the aort valve. However, to date, little is known about the morphological structure of calcification formation in the tissue of the aortic valve. In this study, morphology and structural analysis of calcification in the aorta valve were performed. In addition, the effects of other artifacts were investigated. Scanning electron microscopy (SEM) was used to determine the morphology of calcification structures deposited in aortic valve tissue. Energy Dispersive X-ray Analysis (EDX) and X-ray Diffractometer (XRD) were used to characterize the morphological structures observed by SEM. The results revealed that trace elements play a role in nucleation for the formation of calcification.

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